MEDIThursday, April 10, 2008
9:00 AM-12:20 PM Morial Convention Center -- Rm. 244/245, Oral
General Oral Session
Organizer:James R. McCarthy
9:00 AM329Discovery and SAR of a novel series of orally efficacious antagonists of the CCK-2/gastrin receptor that block gastric acid secretion in vivo
Michael Rabinowitz, Brett D. Allison, Mark Rosen, Victor K. Phuong, Laura C. McAtee, Clogagh Prendergast, Xiaodong Wu, Magda F. Morton, Terrance Barrett, Nigel P. Shankley
9:20 AM330Identification of a new class of nonpeptidic inhibitors of cruzain
Katrien Brak, Patricia S. Doyle, James H. McKerrow, Jonathan A. Ellman
9:40 AM331Bump-hole reoptimization of the tacrine pharmacophore achieves selective inhibition of Anopheles gambiae acetylcholinesterase
Paul R. Carlier, Larry D. Williams, Jeffrey R. Bloomquist, Troy D. Anderson, Sally Paulson, Ania Wysinski
10:00 AM332Benzimidazolones: A new class of PPAR gamma selective modulators
W-G. Liu, K. Liu, T. E. Akiyama, M. Einstein, J. R. Thompson, C. H. Chang, M. E. McCann, J. P. Berger, H. B. Wood, P. T. Meinke
10:20 AM333Crystalline packing: A crucial aspect for developing new cooling agents
Stefan M. Furrer
10:40 AM334Giving the Rule-of-5 a more accurate twist
Sanjivanjit Bhal, Ian G. Peirson, Karim Kassam, Greg Pearl
11:00 AM335Synthesis and biological evaluation of novel cannabinoid receptor ligands
Hong Shu, Sari Izenwasser, Mark L. Trudell
11:20 AM336Targeting T- and B-cell lymphomas: Heterocyclic antagonists for alpha4-beta1 integrin
Richard D. Carpenter, Kit S. Lam, Mark J. Kurth
11:40 AM337Targeting the Polo Box Domain of Polo-like kinase 1 for therapeutics
Karen M. Carter, Peter Wipf
12:00 PM338Structure guided design of balanced dual PPARalpha/gamma agonists for the treatment of type II diabetes and dyslipidemia
Uwe M. Grether, Hans Hilpert, Bernd Kuhn, Hans Peter Marki, Markus Meyer, Peter Mohr

Symposium Grid -- Division of Medicinal Chemistry -- Session Listing

The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008