ORGNTuesday, April 8, 2008
8:00 AM-12:00 PM Morial Convention Center -- Rm. R05, Oral
Biologically Active Molecules
Synthesis and Process Chemistry
Presiding:Michael B. Smith
8:00 AM272Efforts toward the total syntheses of β-C-glycoside natural products via oxocarbenium cations
Michael P. Jennings
8:20 AM273A practical enantioselective synthesis of a potent dual PPAR alpha/gamma agonist
Xinhua Qian, Rajendra P. Deshpande, Erqing Tang, Junying Fan, Keming Zhu, Shirley Wong, Jingyang Zhu, Jale Muslehiddinoglu
8:40 AM274Microwave-assisted synthesis of near-infrared sphingosine derivatives for cell labeling
Kumar R. Bhushan, Preeti Misra, John Frangioni
9:00 AM275New synthetic sugar-nucleotide donor substrates for glycosyltransferases
Maria R. Manzoni, Elizabeth Boeggeman, Boopathy Ramakrishnan, Marta Pasek, Pradman Krishen Qasba
9:20 AM276Process development efforts toward a scalable synthesis of a next generation statin
Michael M. Miller, Lindsay Hobson, Kishta Katipally, Robert Livingston, Jan Spink, Kana Yamamoto, Otute Akiti, Subodh Deshmuk, Shannon Harper, Ehrlic Lo, Srinivas Tummala, John Young, Rodney L. Parsons Jr.
9:40 AM277Synthesis and biological evaluation of triazole-linked glycopeptides
Floris P. J. T. Rutjes, Brian HM. Kuijpers, Stan Groothuys, Floris L van Delft
10:00 AM278Synthesis and pKa values of stereoelectronically diverse methylenebisphosphonic acids: A nucleotide analog toolkit to probe nucleic acid polymerase structure and function
Thomas G. Upton, Jorge Osuna, Boris A. Kashemirov, Charles E. McKenna, Myron F. Goodman, Christopher A. Sucato, Samuel H. Wilson, Vinod K. Batra, Lars C. Pedersen, William A. Beard
10:20 AM279Synthesis of β-(1→2)-linked mannopyranosides and their analogs
Monika Poláková, Mattias U. Roslund, Tiina Saloranta, Filip Ekholm, Kaisa Nieminen, Johannes Savolainen, Reko Leino
10:40 AM280Synthesis of oligosaccharides derived from Burkholderia pseudomallei and mallei: Potential agents for bioterrorism
Alok S. Mehta, Geert-Jan Boons
11:00 AM281Synthesis of Se-thymidine phosphoramidites and their incorporation into oligonucleotides for structural and functional study of nucleic acid
Jia Sheng, Jozef Salon, Jiansheng Jiang, Zhen Huang
11:20 AM282Synthesis of water soluble N-acyl chitosan derivatives for characterization as antibacterial agents
Lakia M. Champagne, William H. Daly
11:40 AM283Using Quality by Design to control genotoxic impurities and develop a manufacturing route to Factor Xa inhibitor apixaban
Lucius T. Rossano, Boguslaw M. Mudryk, Nicolas Cuniere, Jing Liang, Srinivas Tummala, Adrian David, Praveen Sharma, Bing-Shiou Yang, James Sherbine

Biologically Active Molecules -- Next Session

Symposium Grid -- Division of Organic Chemistry -- Session Listing

The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008