CARBSunday, April 6, 2008

8:20 AM-1:20 PM Morial Convention Center -- Rm. 214, Oral
RNA as a Drug Target
Presiding:Muthiah Manoharan
Organizer, Presiding:Daniel H. Appella
8:20 AMIntroductory Remarks
8:25 AMRNA Targeting with 2′ -Fluoro-2′ -deoxyarabinonucleic acids (2′F-ANA)
Masad J. Damha, JK. Watts, N. Bayó, J. Lackey, G. Deleavey, N. Wazen, M. El-Sabahy, JC. Leroux
9:05 AMTherapeutic strategies using RNA interference pathways: Targeting RNA by RNA and RNA analogs
Muthiah Manoharan
9:45 AMExploring RNA–ligand interactions
Yitzhak Tor
10:25 AMDiscovery of new ligands for ribosomal RNA targets
Christine S. Chow
11:05 AMIntermission
11:20 AMFunctionalized polyamines with selective binding to TAR RNA
Daniel H. Appella
12:00 PMProbing the thermodynamics and conformational dynamics of drug-RNA interactions: Amionglycoside targeting the rRNA A-site
Daniel S. Pilch
12:40 PMTargeting hepatitis C virus RNA
Thomas Hermann

Symposium Grid -- Division of Carbohydrate Chemistry -- Session Listing

The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008