Alkali metal in silica gel: A new route to access derivatized diarylphosphines

ORGN 536

Partha Nandi, nandipar@msu.edu1, James L. Dye, dye@signachem.com2, Michael Lefenfeld, michael@signachem.com2, and James E. Jackson1. (1) Department of Chemistry, Michigan State University, East Lansing, MI 48824, (2) SiGNa Chemistry, 530 East 76th Street, Suite 9E, New York, NY 10021
Diarylphosphides are important building blocks for organic and organometallic syntheses and catalysis. This talk will illustrate the application of alkali metal absorbed in silica gel in the reductive cleavage of triarylphosphine and subsequent functionalization of diarylphosphides. The role of electron density on the aromatic rings, different electrophiles, solvent effects will be showcased. In addition the role of ethylenediamine and other electron transporters as catalysts will be described.
 

Materials, Devices and Switches, Metal-Mediated Reactions, Asymmetric Reactions, Total Synthesis, Biologically-Related Molecules and Processes
7:00 PM-9:00 PM, Wednesday, April 9, 2008 Morial Convention Center -- La Louisiane, Blrm. C, Poster

Division of Organic Chemistry

The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008