Synthesis of large and small molecules using olefin metathesis catalysts

ORGN 270

Robert H. Grubbs, rhg@caltech.edu, Division of Chemistry and Chemical Engineering, Arnold and Mabel Beckman Laboratory of Chemical Synthesis, California Institute of Technology, 1200 E. California Blvd., Pasadena, CA 91125
Ruthenium based olefin metathesis catalysts have provided new routes to olefins that appear in a variety of structures. Their functional group tolerance and ease of use allow their application in the synthesis of multifunctional bioactive molecules. The same systems are also useful for the synthesis of an array of new materials from multifunctional polymers to supramolecular systems. Underlying these developments has been the discovery of active catalysts with controlled selectivity based on the synthesis of new ligands.
 

Elias J. Corey Award for Outstanding Original Contribution in Organic Synthesis by a Young Investigator: Symposium in Honor of F. Dean Toste
8:30 AM-12:00 PM, Tuesday, April 8, 2008 Morial Convention Center -- La Nouvelle, Blrm. C, Oral

Division of Organic Chemistry

The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008