ORGN 113 |
| We have recently developed a new, versatile and stereocontrolled approach to the synthesis of α-amino alcohols based on a three-component reaction between amines, α-hydroxy carbonyl compounds and organoboron derivatives. Many applications of this chemistry have also been reported. Herein, we report the use of this type of three-component process to produce suitably substituted amino alcohols that can be subsequently subjected to an intramolecular Friedel-Crafts process to form novel heterocycles. |
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Physical Organic Chemistry, Combinatorial and Process Chemistry, New Reactions and Methodology, Peptides, Proteins and Amino Acids
8:00 PM-10:00 PM, Sunday, April 6, 2008 Morial Convention Center -- Hall A, Poster
Division of Organic Chemistry |