Enantioselective, organocatalytic reduction of ketones using bifunctional amine/thiourea catalyst

ORGN 16

J. R. Falck, J.Falck@UTSouthwestern.edu, Departments of Biochemistry and Pharmacology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390 and Derun Li, derun.li@utsouthwestern.edu, Departments of Biochemistry and Pharmacology, University of Texas, Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390.
A new, air-stable bifunctional catalyst mediates the asymmetric reduction of ketones by catecholborane. The scope and mechanistic insight will be discussed.

 

Asymmetric Reactions and Syntheses
8:00 AM-12:00 PM, Sunday, April 6, 2008 Morial Convention Center -- Rm. R06, Oral

Division of Organic Chemistry

The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008