Versatile water-soluble deep-cavity cavitands

ORGN 392

Sarah E. Whisenhunt, swhisenh@uno.edu and Bruce C. Gibb, bgibb@uno.edu. Department of Chemistry, University of New Orleans, 2000 Lakeshore Dr, New Orleans, LA 70148
Deep-cavity cavitand 1 self-assembles in basic aqueous media to form well-defined nano-capsules. It thus provides a unique system for binding and encapsulation studies in aqueous solution. We will report on work aimed at expanding the utility of this cavitand by coating it with amino acids (e.g., 2). In particular, we will report on cavitands that are soluble across the pH range, and are therefore capable of encapsulating a broader range of guests. Additionally, we will report on the assembly of cavitands that differ in the nature of R2, and discuss the properties of the resulting hetero-capsules.

 

Heterocycles and Aromatics, Molecular Recognition and Self Assembly
8:00 PM-10:00 PM, Tuesday, April 8, 2008 Morial Convention Center -- Hall A, Poster

Division of Organic Chemistry

The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008