ORGN 549 |
| 1-Azatriptycene is a compound with a di-π-methane system, similar to triptycene, except that one of the bridgehead methane positions contains nitrogen instead of carbon. Synthesis of 1-azatriptycene was first published in 1964 via the internal nucleophilic addition to a benzyne. Our study involves synthesis of an azatriptycene through palladium catalyzed amination of arenes (the Buchwald-Hartwig reaction). In the synthetic route under current investigation, the desired azatriptycene has a methyl substituent in the 6-position to avoid unwanted side reactions. This poster presents our progress towards the synthesis of 1-azatriptycenes.
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Materials, Devices and Switches, Metal-Mediated Reactions, Asymmetric Reactions, Total Synthesis, Biologically-Related Molecules and Processes
7:00 PM-9:00 PM, Wednesday, April 9, 2008 Morial Convention Center -- La Louisiane, Blrm. C, Poster
Division of Organic Chemistry |
