ORGN 556 |
| Conjugated p-electron systems represent one of the most important classes of transduction materials that transform a chemical signal to an easily measurable electrical or optical output. This is due to the fact that their important properties such as charge transport, emission intensity and efficiency of exciton migration can be simply attenuated by external stimuli, leading to considerable changes in observable signals. We have developed a general approach to ratiometric (color changing) fluorescent sensors. The operative principle of these sensors is based on the ability to efficiently control the photoexcitation energy transfer in extended p-conjugated system by analyte binding. Herein we report the synthesis and study of pH responsive ratiometric fluorescent sensor designed based on this approach that is composed of oligo(p-phenylene-ethynylene) unit as a conjugated core terminated with fluorescein as a pH sensing unit. |
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Materials, Devices and Switches, Metal-Mediated Reactions, Asymmetric Reactions, Total Synthesis, Biologically-Related Molecules and Processes
7:00 PM-9:00 PM, Wednesday, April 9, 2008 Morial Convention Center -- La Louisiane, Blrm. C, Poster
Division of Organic Chemistry |