ORGN 78 |
| The use of insect repellents can play a key role in the prevention of insect-borne illnesses in humans and animals such as West Nile Virus and Malaria. In spite of the widespread use of N,N-diethyl-m-toluamide (DEET)-containing insect repellents, the search for new effective repellents active against a wide diversity of insect species continues to be an active area of research. One approach involves the exploitation of naturally-derived repellents such as the monoterpene nepetalactone found in the essential oil of the catmint plant. Hydrogenation of catmint oil converts the nepetalactone diastereomers present into a mixture dihydronepetalactone (DHN) diastereomers and the product obtained is a safe and effective insect repellent for human topical use. The synthesis and repellency of the major DHN diastereomers present in hydrogenated catmint oil will be presented and discussed. |
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Physical Organic Chemistry, Combinatorial and Process Chemistry, New Reactions and Methodology, Peptides, Proteins and Amino Acids
8:00 PM-10:00 PM, Sunday, April 6, 2008 Morial Convention Center -- Hall A, Poster
Sci-Mix
Division of Organic Chemistry |