ORGN 219 |
| Enyne metathesis has become a synthetically powerful method for the catalytic synthesis of conjugated dienes. The enyne metathesis furnishes dienes which can be functionalized by cycloadditions. However, the availability of additional, distinct functionalization reactions will increase the versatility of the diene synthesis. In this presentation, the development of a new acid promoted diene functionalization reaction is described. Our findings demonstrate that this is an effective synthesis for a variety of heterocycles and can be conducted in an efficient, one-pot transformation. |
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Metal-Mediated Reactions and Synthesis
8:00 AM-12:00 PM, Monday, April 7, 2008 Morial Convention Center -- Rm. R06, Oral
Division of Organic Chemistry |