First facile total synthesis of methylgerambullone

ORGN 602

Jong Taik Moon, orgphoto@nate.com1, Chun Rim Oh, ohcr@lycos.co.kr2, Young Deuk Kim, angelson@hanmail.net2, Dong Joon Choo, djchoo@khu.ac.kr1, and Jae Yeol Lee, ljy@khu.ac.kr1. (1) Department of Chemistry, Kyung Hee University, 1 Hoegi-Dong, Dongdaemun-Gu, Seoul, 130-701, South Korea, (2) DongWoo Syntech, Co., Ltd, 152-1, Bondae-Ri, Geumwang-Eup, Eumsung-Goon, Choongcheungbook-Do, 369-901, South Korea
Methylgerambullone was one of the compounds that were isolated from the methanolic leaf of Glycosmis angustifolia collected in Sri Lanka. Herein, we wish to report the first total synthesis of Methylgerambullone by an efficient construction and coupling of three segments.

 

Materials, Devices and Switches, Metal-Mediated Reactions, Asymmetric Reactions, Total Synthesis, Biologically-Related Molecules and Processes
7:00 PM-9:00 PM, Wednesday, April 9, 2008 Morial Convention Center -- La Louisiane, Blrm. C, Poster

Division of Organic Chemistry

The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008