ORGN 32 |
| A systematic study on the structure/reactivity relationships of bicyclic epoxonium ions towards tethered nucleophiles has been conducted. The cyclization results show that bicyclo[4.1.0] epoxonium ions have a strong preference for endo-cyclization while bicyclo[3.1.0] epoxonium ions have a significant to exclusive preference for exo-cyclization. This method is currently being applied to the total synthesis of (-)-lactodehydrothyrsifeol.
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New Reactions and Methodology
8:00 AM-12:00 PM, Sunday, April 6, 2008 Morial Convention Center -- Rm. R04, Oral
Division of Organic Chemistry |
