Water-soluble benzophenoxaziminium dyes: Syntheses and photophysical properties

ORGN 394

Yuichiro Ueno, yueno@mail.chem.tamu.edu, Department of Chemistry, Texas A&M University, 3255 TAMU Chemistry, College Station, TX 77843, Jiney Jose, jjose@mail.chem.tamu.edu, Department of Chemistry, Texas A&M University College Station, 3255 TAMU Chemistry, College Station, TX 77843, and Kevin Burgess, burgess@tamu.edu, Department of Chemistry, Texas A & M University, Box 30012, College Station, TX 77842-3012.
Benzophenoxaziminium dyes (also called Nile Blue) are highly useful chromphore for bioimaging in the field of biochemistry and medicinal chemistry. Many researchers have been synthesizing these dyes because of its excellent photo stability and high emission wavelength. Water-soluble derivatives are even more desirable for bioimaging studies. Our efforts toward the improving photophysical properties using different water-solubilizing groups will be presented. Photophysical properties of these dyes on a protein will also be presented.