ORGN 40 |
| Multi-component processes, domino reactions and sequential transformations are diversity oriented syntheses and have considerably stimulated the synthetic scientific community. In particular, multi-component reactions (MCR) have found broad application in pharmaceutical high-throughput screening and lead finding. Surprisingly, MCR and domino reactions are still in their infancy with respect to the discovery and development of functional &pi-electron systems, such as chromophores, fluorophores and redox active molecules. Within the last decade there have been adaptations of several diversity-oriented approaches. In particular, transition metal catalyzed reactions have proven to be an excellent entry to multi-component and domino syntheses of chromophores and fluorescent materials. The reactivity based concept of transition metal catalyzed diversity oriented syntheses of functional &pi-electron systems will be introduced and discussed. |
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Novel Fluorophores
1:00 PM-5:30 PM, Sunday, April 6, 2008 Morial Convention Center -- Rm. R05, Oral
Division of Organic Chemistry |