ORGNThursday, August 23, 2007

8:00 AM-12:00 PM BCEC -- 254 A/B, Oral
Heterocycles and Aromatics
Presiding:Scott McN. Sieburth
8:00 AMA new and efficient preparation of 2-aminothiazole-5-carbamides, applications to the synthesis of Dasatinib, a new potent pan-src kinase inhibitor
Bang-Chi Chen, Rulin Zhao, Bei Wang, Robert Droghini, Jean Lajeunesse, Pierre Sirard, Masaki Endo, Balu Balasubramanian, Joel C Barrish
8:20 AMKilogram synthesis of a LFA-1/ICAM inhibitor
Albert J. DelMonte
8:40 AMA regiospecific synthesis of N-aryl and N-alkyl benzimidazoles
Nan Zheng, Kevin W. Anderson, Xiaohua Huang, Hanh Nho Nguyen, Stephen L. Buchwald
9:00 AMOrigins of selectivity in Pd-catalyzed C-N bond-forming reactions using biarylphosphine ligands
Mark R. Biscoe, Timothy E. Barder, Stephen L. Buchwald
9:20 AMCombined directed metalation and cross coupling tactics: A new carbanionic indole N-carbamoyl translocation reaction
Victor Snieckus, Katherine A. Groom, Zhongdong Zhao
9:40 AMHighly regioselective syntheses of N1-substituted and N2-substituted 1,2,3-triazoles
Sen Wai Kwok, Jason Hein, Valery V. Fokin, K. Barry Sharpless
10:00 AMIsomeric diazadienes via the Lewis acid-mediated isomerization of methylenecyclopropyl hydrazones
Mark E. Scott, Yann Bethuel, Mark Lautens
10:20 AMTandem benzannulation cyclization strategy for the synthesis of highly-substituted indoles
Tin Yiu Lam, Rick L. Danheiser
10:40 AMTandem benzannulation ring-closing metathesis strategy for the synthesis of benzo-fused nitrogen heterocycles
Xiao Yin Mak, Aimee L. Crombie, Rick L. Danheiser
11:00 AMWhat are the requirements for monohomoaromatic carbocations with ≥10 π electrons? A DFT study
Philip M. Warner
11:20 AMWhat is the π electron size limit for neutral bishomoaromaticity?: a DFT study
Philip M. Warner
11:40 AMN-Heterocyclic carbene (NHC) catalyzed synthesis of isoxazolidin-5-ones and a one-pot synthesis of β-amino acid esters
Jayasree Seayad, Pranab K. Patra, Yugen Zhang, Jackie Y Ying

Heterocycles and Aromatics -- Next Session

Symposium Grid -- Division of Organic Chemistry -- Session Listing

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007