Facile synthesis of alpha-ionone and its analogs

ORGN 761

D. W. Rangnekar, dwrangnekar@yahoo.com1, V. S. Kulkarni, drvskulkarni@rediffmail.com1, P. V. Ranade1, and R. W. Sabnis, ramsabnis@yahoo.com2. (1) Institute of Chemical Technology, University of Mumbai, Matunga, Mumbai, 400019, India, (2) Squire, Sanders & Dempsey LLP, One Maritime Plaza, Suite 300, San Francisco, CA 94111-3492
Synthesis of alpha-ionone and its analogs, the commercially important aroma compounds, have been accomplished from the readily available 3,5,5-trimethyl-2-cyclohexen-1-ol via a short, facile, and simple sequence of reactions in excellent yield