Expanding the scope of microwave-promoted synthesis

ORGN 45

Nicholas E. Leadbeater, nicholas.leadbeater@uconn.edu, Department of Chemistry, University of Connecticut, 55 North Eagleville Road, University of Connecticut, Storrs, CT 06269-3060
In this lecture, results from ongoing programs in the area of microwave-promoted chemistry will be presented. These include challenges and opportunities in scale-up of reactions, development of tools for in-situ reaction monitoring, microwave heating in biofuel manufacture and new method development for organic chemistry. Specifically - Scale-up: Suzuki reactions, dihydropyridine synthesis, Beckmann rearrangements. In-situ monitoring: Use of Raman spectroscopy as a tool for optimization of microwave promoted reactions. Biofuels: Taking the microwave-promoted synthesis of biodiesel from batch to process scale. New method development: Reactions under an atmosphere of reactive gas.