ORGN 911 |
| This talk will describe new beta-helical scaffolds derived from peptides composed of alternating D- and L-amino acids. Although beta helices have been known for decades—a prominent example is the transmembrane-pore-forming antibiotic gramicidin A—many opportunities remain for exploiting these structures in bioorganic chemistry. A number of designed beta-helical peptides will be presented, and results from CD, IR, NMR, and computer modeling will be discussed.
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Proteins, Peptides, Amino Acids, and Enzyme Inhibitors
8:00 AM-12:00 PM, Thursday, August 23, 2007 BCEC -- 258B, Oral
Division of Organic Chemistry |
