ORGN 822 |
| This paper reports a new method for monitoring chemical reactions on solid phase. The method is simple, inexpensive, and does not require labeling of resins or reagents. In addition, the method is sufficiently sensitive that resin-bound small molecules can be distinguished (and separated) when they differ only by a single atom. The method is based on the concept of diamagnetic levitation, and requires two small magnets and a solution containing a paramagnetic salt; no electricity is needed, and the device takes up less space than a hot plate. We anticipate that this device will become an indispensable tool both for academic laboratories and for pharmaceutical companies. |
|
Combinatorial, Parallel and Process Chemistry, Heterocycles, Aromatics, New Reactions and Methodology
8:00 PM-10:00 PM, Wednesday, August 22, 2007 BCEC -- Exhibit Hall - B2, Poster
Division of Organic Chemistry |