Catalytic synthesis of 5-amino-oxazoles and chiral heterocycles from isonitriles and imines

ORGN 747

Amal Ting, amalting@bu.edu and Scott E. Schaus. Department of Chemistry, Boston University, Life Science Engineering Building, 24 Cummington Ave., Boston, MA 02115
Isonitriles serve as reactive precursors for heterocycle synthesis. This presentation will describe the use of isonitriles in the construction of 5-amino-oxazoles and chiral heterocycles from imines. The use of Brønsted acids and metal catalysts will be highlighted.