Facile preparation of new polyfunctional pyrrolidinones from 3-hydroxyitaconate alkyl diesters

ORGN 759

Jean-Francois Morizur, jean.morizur@usm.edu, School of Polymers and High Performance Materials, University of Southern Mississippi, Southern Mississippi, Box 10076, Hattiesburg, MS 39406-0076, Hattiesburg, MS 39406 and Lon J. Mathias, lon.mathias@usm.edu, Department of Polymer Science, The University of Southern Mississippi, USM Mailbox 10076, Hattiesburg, MS 39406.
The synthesis of new hydroxyitaconate diesters via the Bayllis-Hillmann reaction pathway is described. These activated alkenes present an extremely high reactivity upon Michael addition with primary amines leading to a simple, mild and efficient route to the preparation of new polyfunctional pyrrolidinones.

 

Combinatorial, Parallel and Process Chemistry, Heterocycles, Aromatics, New Reactions and Methodology
8:00 PM-10:00 PM, Wednesday, August 22, 2007 BCEC -- Exhibit Hall - B2, Poster

Division of Organic Chemistry

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007