Ni/NHC-catalyzed preparation of unsymmetrical oligophenyls

ORGN 543

Chul-Bae Kim, kchulbae@hotmail.com1, Chang Keun Kim, ckkim@cau.ac.kr1, and Kwangyong Park, kypark@cau.ac.kr2. (1) School of Chemical Engineering and Materials Science, Chung-Ang University, 221 Heuksuk-Dong, Dongjak-Gu, Seoul, 156-756, South Korea, (2) School of Chemical and Materials Science, Chung-Ang University, Huksuk-Dong 221, Dongjak-Ku, Seoul, 156-756, South Korea
The nickel-catalyzed cross-coupling reactions of neopentyl arenesulfonates and pentaerythritol tetrakis(benzenesulfonate)s with alkyl or aryl Grignard reagents produced unsymmetrical biphenyl and terphenyl derivatives, which are of great interest due to their biological and optical properties, in the presence of a Ni/N-heterocyclic carbene (NHC) catalyst. Ni/NHC catalyst could allow the coupling reaction to undergo at room temperature within a short period of time, which would make this reaction useful for the solid-phase or solution-phase parallel/combinatorial chemistry.
 

Physical Organic Chemistry, Metal-Mediated Reactions, Asymmetric Reactions and Syntheses
8:00 PM-10:00 PM, Tuesday, August 21, 2007 BCEC -- Exhibit Hall - B2, Poster

Division of Organic Chemistry

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007