ORGN 33 |
| In an effort to develop novel treatments for the reduction of serum cholesterol, a series of biologically active azetidinones was discovered. The optimization of these leads, and further discovery of Zetia, a first in class drug for the treatment of elevated LDL in man, will be discussed. Recent results from the in vitro SAR and the elucidation of the mechanism of action studies will be included. |
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ACS Award for Creative Invention: Symposium in Honor of Bruce Ganem
1:30 PM-5:00 PM, Sunday, March 25, 2007 McCormick Place Lakeside -- Room E450 A/B, Level 4, Oral
Division of Organic Chemistry |