Studies toward the total synthesis of fusidilactone C

ORGN 422

Sunil K. Ghosh, sghosh2@wisc.edu, Yonggang Wei, ywei2@wisc.edu, Jiashi Wang, and Richard P. Hsung. School of Pharmacy, UW Madison, 777 Highland Ave., Madison, WI 53705
The progress of the total synthesis of Fusidilactone C is described here. A rare ketal-tethered intramolecular Diels-Alder cycloaddition is involved for the synthesis of the 2-oxadecalin spiroketal core of Fusidilactone C.