ORGN 754 |
| The ring-closing metathesis (RCM) of dendrimers was studied to determine the dynamic nature of the process and whether mechanical intertwining (catenation) was occurring. To examine the reaction in detail, three dendrimers were synthesized and cross-linked using 1st and 2nd generation Grubbs catalyst. Dendrimer 1 contained a pre-cross-linked portion and a portion with monosubstituted alkenes. Dendrimer 2 contained two pre-crosslinked portions with only disubstituted alkenes. To test whether catenation was occurring, dendrimer 3 containing a hydrogenated portion and a portion with monosubstituted alkenes was synthesized. After cross-linking, the dendrimers were hydrolyzed and the products analyzed by analytical SEC and MALDI-TOF MS to determine whether the dendrimers remained intact or fragmented.
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Materials, Devices, and Switches
8:00 AM-12:00 PM, Thursday, March 29, 2007 McCormick Place Lakeside -- Room E450 A/B, Level 4, Oral
Division of Organic Chemistry |
