Ring opening-closing metathesis of 7-azanorbornene and the applications in the studies of total synthesis toward rostratins

ORGN 419

Zhuqing Liu, zliu@chem.utah.edu and Jon D. Rainier, rainier@chem.utah.edu. Department of Chemistry, University of Utah, 315 So. 1400 E, Salt Lake City, UT 84112
Rostratins (A-D) were isolated by Fenical group. In this poster, we describe methodology – ring opening and closing metathesis of 7-azanorbornenes to generate the core structure of the rostratins as well as further studies targeting their total synthesis.