ORGN 116 |
| Noncovalent interactions involving aromatic rings are key processes in chemical and biological recognition. While the concept of attractive l.p.-p interaction is counterintuitive, this type of attraction was observed by crystallographic evidence. H2O (lp)-p (cytosine) interaction in an RNA pseudoknot has been reported. Recent ab initio studies indicate that lp-p interaction is favorable with electron-deficient p-systems. For the first time, we are able to determine the magnitude of this weak interaction using our model system. Substituent effects and contact geometry will be discussed.
|
|
Process R&D, Physical Organic Chemistry, Heterocycles, Aromatics, Metal-Mediated Reactions
8:00 PM-10:00 PM, Sunday, March 25, 2007 Hyatt Regency Chicago -- Riverside Center, Poster
Division of Organic Chemistry |
