ORGN 627 |
| The diversity and reliability of organometallic reactions has increased greatly over the last few decades, and it is commonplace to see such reactions in high throughput and process chemistry environments. The removal of active metal reagents or residues is essential to provide clean and safe compounds for screening. We have developed a range of polymeric materials suitable for metal sequestration and have proven their efficacy for commonly used metals, such as palladium, ruthenium, platinum and tin. In order to expand these studies to encompass all synthetically useful metals, a large combinatorial study was undertaken using a range of functional polymers. This exercise was only possible using modern, high throughput ICP analysis techniques and instrumentation. Herein, we will describe definitive polymer selection criteria for effective scavenging of a large range of metal species. |
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Asymmetric Reactions, Combinatorial Chemistry, Molecular Recognition and Self-Assembly, Proteins, Peptides, Amino Acids and Enzyme Inhibitors
8:00 PM-10:00 PM, Wednesday, March 28, 2007 Hyatt Regency Chicago -- Riverside Center, Poster
Division of Organic Chemistry |