ORGN 695 |
| Covalent attachment of a template via a phosphonic acid group was the first step in the preparation of imprinted silica gel surfaces. Organotrialkoxysilanes with complementary binding groups were then attached as shown below, followed by template removal by treatment with aqueous HCl. Model template and binding molecule attachment to the surface and subsequent removal of the template were confirmed by infrared spectroscopy. Binding isotherms were generated for template-related molecules.
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Asymmetric Reactions, Combinatorial Chemistry, Molecular Recognition and Self-Assembly, Proteins, Peptides, Amino Acids and Enzyme Inhibitors
8:00 PM-10:00 PM, Wednesday, March 28, 2007 Hyatt Regency Chicago -- Riverside Center, Poster
Division of Organic Chemistry |
