ORGN 239 |
| Flow reactors offers many fundamental and practical advantages of relevance to the pharmaceutical industry; who are searching for controllable, high throughput, environmentally friendly methods of rapidly producing products with a high degree of chemical selectivity. In this presentation a number of solution phase chemical reactions will be used to illustrate the advantages that flow reactors offer for the rapid optimisation of reactions, in which the products are produced in both higher yield and purity. The presentation will be extended to show how the incorporation of a wide variety of solid supported reagents, catalysts and scavengers enables purification to be eliminated as analytically pure compounds are obtained. By developing a synthetic toolbox of reactions it will be illustrated how the methodology may be used to prepare complex molecules. |
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Combinatorial and Process Chemistry
8:00 AM-11:40 AM, Monday, March 26, 2007 McCormick Place East -- Room E350, Level 3, Oral
Division of Organic Chemistry |