Selection, replication and amplification as tools in organic chemistry

ORGN 616

Douglas Philp, dp12@st-andrews.ac.uk, School of Chemistry, University of St Andrews, North Haugh, St Andrews, KY16 9ST, United Kingdom
The development and deployment of self-replicating molecular architectures can potentially revolutionize materials fabrication at the nanometer scale. The emergence of protocols based on molecular replication will deliver synthetic machinery that is capable of directing its own synthesis and cooperating with other similar systems to create an organized hierarchy. Within this broad objective, the development of efficient protocols that allow self-replication, self-organization and emergent behavior within synthetic supramolecular assemblies is essential. This approach to predetermined dynamic behavior has been termed "systems chemistry". This presentation will describe our development and exploitation of molecular systems that are capable of replication by a variety of different pathways. These individual replicating systems can then be used as building blocks within more complex reaction networks within which the replicating entities cooperate in pre-programmed ways.
 

Molecular Recognition and Self-Assembly
1:00 PM-5:00 PM, Wednesday, March 28, 2007 McCormick Place Lakeside -- Room E352, Level 3, Oral

Division of Organic Chemistry

The 233rd ACS National Meeting, Chicago, IL, March 25-29, 2007