Dimerization strategies for the construction of the central core of lomaiviticins

ORGN 405

Srinivas Achanta, sachanta@artsci.wustl.edu, Prashanth Padakanti, pkpadaka@artsci.wustl.edu, and Vladimir B. Birman, birman@wustl.edu. Department of Chemistry, Washington University in St. Louis, Campus Box 1134, One Brookings Drive, St Louis, MO 63130
Lomaiviticins are structurally unique antibiotics displaying powerful activity against Gram-positive bacteria and a wide range of cancer cell lines. Biogenetically inspired dimerization-based approaches to the central core of these targets will be presented.

 

New Reactions and Methodology, Total Synthesis, Materials, Devices and Switches, Lipids, Nucleotides and Mimetics
8:00 PM-10:00 PM, Tuesday, March 27, 2007 Hyatt Regency Chicago -- Riverside Center, Poster

Sci-Mix
8:00 PM-10:00 PM, Monday, March 26, 2007 Hyatt Regency Chicago -- Riverside Center, Sci-Mix

Division of Organic Chemistry

The 233rd ACS National Meeting, Chicago, IL, March 25-29, 2007