ORGN 721 |
| We have previously reported the utility of pyrazolidinone auxiliaries in a number of enantioselective transformations including dipolar cycloadditions, Diels-Alder cycloadditions, and conjugate additions. Much of this past effort has focused on additions to β-substituted α,β-unsaturated pyrazolidinone imides. Currently, we are interested in expanding the use of pyrazolidinone auxiliaries to more challenging substrates and reactions. Enantioselective transformations of particular interest include: cycloadditions to alkynoates, exo-selective Diels-Alder reactions, and addition reactions to α-substituted α,β-unsaturated substrates. Results demonstrating the use of pyrazolidinone auxiliaries to address these areas of interest will be presented.
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Asymmetric Reactions, Combinatorial Chemistry, Molecular Recognition and Self-Assembly, Proteins, Peptides, Amino Acids and Enzyme Inhibitors
8:00 PM-10:00 PM, Wednesday, March 28, 2007 Hyatt Regency Chicago -- Riverside Center, Poster
Division of Organic Chemistry |
