ORGN 133 |
| 1-Phenylselenyl-1-alkynes easily prepared by the deprotonation of the corresponding terminal alkynes followed by treatment with phenylselenyl chloride, readily react with dichloroborane-dioxane complex in dichloromethane at room temperature for 12 h. The resulting solution is then treated with 1,3-propane diol at 0 oC for half an hour to provide the corresponding (Z)-1-phenylselenyl-1-alkenylboronate esters in high yields (72%-83%) and the oxidation studies of these intermediates are currently in progress.
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Process R&D, Physical Organic Chemistry, Heterocycles, Aromatics, Metal-Mediated Reactions
8:00 PM-10:00 PM, Sunday, March 25, 2007 Hyatt Regency Chicago -- Riverside Center, Poster
Division of Organic Chemistry |