BIOTThursday, 14 September 2006

8:00 AM-11:00 AM Hilton San Francisco -- Plaza, Oral
Downstream Processing: Downstream Process Modeling to Facilitate Process Development, Validation and Troubleshooting
Organizers:Ajoy Velayudhan
Manoj Menon
8:00 AMIntegration of experimental and modeling approaches to extend the utility of bioprocess chromatography simulation
Daniel G. Bracewell, Eva Sorensen, Nigel Titchener-Hooker
8:20 AMOptimization of productivity and process economics of Protein A column chromatography
Michael W. Phillips, Chen Wang, Ryan Manetta
8:40 AMFormulation and application of a theoretical model for chromatography column scale-up
Justin T McCue, James Weidner, Cathy Chu, Andrew Spann, Nia Beckley, Rachel Williams
9:00 AMModeling critical constraints in the Downstream Process
Charles A. Siletti, D. Petrides
9:20 AMIntermission
9:40 AMModeling and simulation of ion-exchange chromatography processes for purification of biopharmaceuticals
Shuichi Yamamoto, Peter K Watler, Oliver Kaltenbrunner
10:00 AMUsing elasticity theory to predict limits on mobile phase velocity and pressure drop for manufacturing-scale column operation
Ronald N. Keener III, Erik J. Fernandez, Roger Hart
10:20 AMScale-up modeling of pressure flow behavior of semi-rigid biochromatography resins
Grant W. Espie, Tessa L. Chao, Daniela Fluture
10:40 AMVmax Nomograph: A tool for rapid filter sizing
Bala Raghunath

Symposium Grid -- Division of Biochemical Technology -- Session Listing

Symposium Grid -- Biotech -- Session Listing

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006