ORGNWednesday, 13 September 2006

8:00 PM-10:00 PM Moscone Center -- Hall D, Poster
Total Synthesis, Materials, Molecular Recognition, Process R&D, and Physical Organic Chemistry
Organizer:Robert D. Larsen
Linear synthesis of α,β-epoxysulfoxides
Marco Antonio Perez Espino
Total synthesis of antibiotic pestalone by using novel pathway
Yudao Ma, Yongchang Chen, Zhijun Sun, Qiang Chai, Minghu Huang, Changqin Ma, Xi Fang, Chun Song
Chemical studies toward the total synthesis of Azaspirene, a novel angiogenesis inhibitor
Amer El-Batta, Mikael Bergdahl
Studies toward the total synthesis of 2′-O-methylmyxalamide D and its geometric isomers
Robert S. Coleman, Xiaoling Lu
Paper Withdrawn
Studies towards a synthesis of oseltamivir phosphate (Tamiflu®) via an allenolate cyclization
Rachel N. MacCoss, Erik J. Sorensen
Progress towards the total synthesis of Laurenditerpenol, an HIF-1 inhibitor
Michael E. Jung, G-Yoon Jamie Im
Studies toward the total synthesis of fomannosin
Xiaowen Peng, Leo A. Paquette
Progress towards the synthesis of Laureatin
Christopher D. Taylor, Bernard F. Castillo II, Amy R. Howell
Neurotrophic factors and the treatment of neurodegenerative diseases: Studies on the total synthesis of kirkinine, a uniquely potent neurotrophic agent
Paul A. Wender, F. Christopher Bi, Nicole Buschmann, Francis Gosselin, Cindy Kan, Jung-Min Kee, Hirofumi Ohmura
Progress towards the total synthesis of gnidimacrin: Synthesis of the tricyclic core and macrocycle precursor
Paul A. Wender, Noel D. D'Angelo, Vassil I. Elitzin, Martin Ernst, Eileen E. Jackson-Ugueto, John A. Kowalski, Sharon McKendry, Markus Rehfeuter, Robert Sun, David Voigtlaender
In pursuit of pestalotiopsin A via zirconocene-mediated ring contraction
Shuzhi Dong, Leo A. Paquette
Progress toward the total synthesis of (-) Arteannuin M
Honghui Wu, Kevin D. Moeller
Total synthesis of smenochromene B
Michael Kienzler, Carla P. D. C. P. Rosa, Brooke Olson, Dirk Trauner
Towards the total synthesis of kidamycin
ZhongBo Fei, Frank E. McDonald
Total synthesis of icetexane diterpenoids via a metal-mediated cycloisomerization
Eric M. Simmons, Richmond Sarpong
Exploiting the whole cell-mediated biotransformation of arenes as a source of enantiomerically pure building blocks for the chemical synthesis of biologically important natural products
Jonathan S. Foot, Martin G. Banwell
Progress towards the asymmetric total synthesis of Eupomatilone 5
Soumya Mitra, Robert S. Coleman
First total synthesis of rottlerin
Marc J. Adler, Steven W. Baldwin
Total synthesis of teuscorolide
Hsing-Jang Liu, I-Chia Chen, Yen-Ku Wu, Jia-Liang Zhu
Pericyclic reaction cascades in biomimetic total synthesis
Jeremiah P. Malerich, Dirk Trauner
Studies toward the total synthesis of cucurbitacins
Blanca J. Gilbes, Fathi T. Halaweish
Progress toward the total synthesis of cardiac glycoside ouabain
Hiufung V. Chu, Michael E. Jung
Efficient synthesis of the bis(tetrahydrofuran) ring core of trilobin and trilobacin and progress toward the synthesis of the natural products
Laura M. Wysocki, Steven D. Burke
Total synthesis of allosamizoline, towards allosamidin
Carla P. D. C. P. Rosa, Timothy J Donohoe
Acetalization/ring-closing metathesis for synthesis of tetrahydropyran containing natural products thromboxane B2 and spicamycin
Christopher C Marvin, Alexander J. L. Clemens, Michael P. McGuan, Steven D. Burke
Progress toward the total synthesis of bryostatin 1: Emphasis on C17-C27 fragment
Victoria L Wilde, Steven D. Burke
Elucidation of the epothilone binding site: Design, synthesis, and tubulin binding of photo-affinity analogs
Oliver E. Hutt, Jack F. Greiner, Jun Inagaki, Gunda I. Georg
Toward the total synthesis of Ipomoeassin B
Georgia Tsoukala, Robert A. Falconer, Mark Searcey
Towards the synthesis of Rhizoxine D: A stereo selective synthesis of C1-C16 core
Javed Iqbal, Srinivas Padakanti, Manojit Pal, K. Mukkanti
Studies toward the synthesis of tedanolide
Joshua R. Dunetz, Lisa D. Julian, William R. Roush
Towards the total synthesis of the natural product tubulysin D
Jeffrey P. McMahon, Hillary M. Peltier, Jonathan A. Ellman
Progress towards the total synthesis of celogentin C
Joshua S. Grimley, Thomas J. Wandless
Total synthesis of the antifungal natural product (-)-pramanicin
Christopher G. Meyer, Cheol Hwan Yoon, Kyung Woon Jung
Stereocontrolled total synthesis of (–)-kainic acid
Hiroshi Sakaguchi, Hidetoshi Tokuyama, Tohru Fukuyama
Synthetic studies towards salinosporamide A
Isabel Villanueva Margalef, Hon Wai Lam
Indole-isonitrile in the Ugi reaction: Application to the synthesis of Omuralide and Salinosporamide A
Cynthia Gilley, Matthew J. Buller, Yoshihisa Kobayashi
Studies towards the synthesis of Chartelline C and related alkaloids
Evan A. Hecker, Philip D. Magnus
Total synthesis of duocarmycin prodrugs
Meritxell Guinó, Laurence H. Patterson, Mark Searcey
Tandem Michael additions to access highly functionalized [3.2.1]bicyclooctanones: Progress towards a synthesis of gelsemine
Scott Grecian, Jeffrey Aubé
Palladium-catalyzed enantioselective desymmetrization for the total synthesis of hodgkinsine and related structures
Matthew J. Durbin, Michael C. Willis
Formal syntheses of hirsutine and rhynchophylline
Martin Pettersson, Alexander Deiters, Stephen F. Martin
Synthetic studies toward the immunosuppressant FR901483: Facile construction of the azatricyclic skeleton
Suvi T. Simila, Stephen F. Martin
Stereoselective synthesis of remote quaternary centers and stereoselective cyclopropane openings: Applications towards the total synthesis of the Daphniphyllum alkaloids
Ryan M. Harrington, Philip D. Magnus
ROM-RCM sequence as a new approach toward the total synthesis of Lepadin B
Guillaume Barbe, André B. Charette
Synthetic studies towards (+)-symbioimine
Stephen Born, Erin E. Olson, Yoshihisa Kobayashi
Synthesis of the eleven-membered ring of the marine alkaloids, madangamines
Naoki Yamazaki, Yuta Yoshimura, Junji Inoue, Sakae Aoyagi, Chihiro Kibayashi
Synthetic studies toward the Lycopodium alkaloid nankakurine A
Ellen D. Beaulieu, Juliette R. Petersen, Dirk Trauner
Towards an enantioselective synthesis of sparteine from a tetraoxobispidine core
Paul R. Blakemore, Neil R. Norcross, Peter C. Astles
Total synthesis and asymmetric formal synthesis of manzacidin D
D. Bruce Mackay, Roch M. A. Lavigne, Christian Drouin, Jacqueline C. S. Woo
Cation-p bonding in a redox-responsive Wurster's cryptophane
John W. Sibert, Sheel C. Dodani
Directed chemically driven aryl-aryl bond rotation in achiral biaryl lactone synthetic molecular motor
Ying Lin, Bruce P. Branchaud
Synthesis and characterization of donor-acceptor chromophores for efficient, unidirectional electron-transfer
Michael F. Pepitone, Glenn G. Jernigan, Joseph S. Melinger, Oh-Kil Kim
Periplasmic binding proteins as biosensors: A synthetic approach
Amanda P Crochet, Matthew B. Francis, Chad Paavola
Design and synthesis of color-switchable RGB dye
Taichi Ikeda, Amar Flood, Weiqiao Deng, Adides Williams, W. A. Goddard III, J. Fraser Stoddart
Towards macroscopic artificial muscles
Jishan Wu, Ken C-F. Leung, Ja-Young Han, Stuart J. Cantrill, Diego Benitez, J. Fraser Stoddart
Synthesis of 2-nitro-9-(2,2,2-triphenylethylidene)fluorene
HyunJong Kim, Thomas W. Bell, Rolando Procupez
Molecularly designed fluorescent materials
Suk-Wah Tam-Chang, Liming Huang, Wonewoo Seo, Jennifer Helbley
Synthesis and device characterization of functionalized anthradithiophenes
Sankar S. Subramanian, John E. Anthony
Exocyclic and in-ring alkene-containing calix[4]arenes via reaction of a 2-(iodomethyl)calix[4]arene
Jordan L. Fantini, Michael J. Kahlenberg, Kenneth P. Klatt, Lara R. Liou
Synthesis of water-soluble C60 co-polymers
Yuko Iwamoto, Sean Oriana, Yoko Yamakoshi
Small-molecule DNA hybrids (SMDH's): Syntheses and recognition properties
Brian R. Stepp, Julianne Gibbs Davis, Dorothea Li Feng Koh, SonBinh T. Nguyen
Influence of donor and acceptor substituents in the self-assembly of molecular grids based on hydrazone ligands
David J. R. Brook, Manisha Dutta
The functionalization of polymers with gold nanoparticles using reversible supramolecular self-assembly processes
Ivan Aprahamian, Paula Mendes, Ken C-F. Leung, Diego Benitez, J. Fraser Stoddart
Towards the synthesis of 5,6,7,8-tetrahydroacridin-4-ol and quinolin-8-ol derived tripodal receptors
Elleanor Rio C. Andaya, Thomas W. Bell
Study of the binding properties of new water-soluble receptors
Hillary J Van Anda, Richard J Hooley, Julius Rebek Jr.
Synthesis of a proposed chemosensor for nerve agents
Rakesh Kumar Sit, Thomas W. Bell
Development of a chemosensor for creatinine
Nicholas M Hext, Thomas W Bell
Thermal unfolding of water-soluble peptoid oligomer secondary structure
Justin M. Holub, Kent Kirshenbaum
Beta-sheet peptidomimetics inspired by nature
Brian R. Linton, Timothy J. Cashman, Henry R. Brennan, Lauren R. Steffel, Michael H. Reutershan
Peptoid oligomers incorporating N-alkoxy sidechains
Peter A Jordan, Paramjit S. Arora, Kent Kirshenbaum
Beta-hairpin peptides that fold due to fluoroaromatic contacts
Chihui An, Tsz Na Ko, Ahamindra Jain
Nonpeptidic foldamers from amino acids
Petra Tosovska, Hiroko Matsuda, Nicholas G. Angelo, Adam Waxman, Paramjit S. Arora
New synthesis of crescent aromatic oligoamides
Aimin Zhang, Bing Gong
Targeting protein-protein interactions with hydrogen bond surrogate artificial alpha-helices
Laura K. Henchey, Deyun Wang, Paramjit S. Arora
Processable porous materials: Porphyrin coordination polymers based on zinc…nitro recognition
Salimgerey Adilov, Venkat R. Thalladi
Oligosaccharide recognition using polypyrrolic macrocycles as scaffolds
Amanda E. Hargrove, Eric V. Anslyn, Jonathan L. Sessler
Aggregation and Host-Guest chemistry of arylene-imine macrocycles
Thomas S. Hughes, Andrew L. Korich, Samantha E. Bernard
Novel synthesis of 1 and 3-dimensionally nanostructured ionic liquids/aluminum hydroxide composite via supramolecular assembly: Effect of water on the formation of nanostructure
Ho Seok Park, Yun Suk Huh, Won Hi Hong
Mechanically interlocked polymers by olefin metathesis
Diego Benitez, J Fraser Stoddart
Dynamic Borromean ring networks
Claire R. Yates, Diego Benitez, J Fraser Stoddart
Borromean ring compounds
Cari D. Pentecost, Kelly S. Chichak, Andrea J. Peters, Stuart J. Cantrill, J. Fraser Stoddart
Molecular Solomon links
Cari D. Pentecost, Kelly S. Chichak, Andrea J. Peters, Stuart J Cantrill, J. Fraser Stoddart
Design, synthesis and anion binding studies of a series of novel, acyclic anion binding agents
Joanthan L. Sessler, Natalie Barkey, G. Dan Pantos, Philip A. Gale
Synthesis of new generation Near-IR fluorescent squaraine-rotaxanes
Na Fu, Easwaran Arunkumar, Bradley D. Smith
Investigation into the synthesis of Tat-inhibitors
Sailaja Govindaraju, Thomas W Bell
Sensors for catecholamine
Dipti N. Barman, Kristen E. Secor, Timothy E. Glass
Calix[5]arenes: Molecular recognition of carboranes
Thomas E. Clark, Mohamed Makha, Colin L. Raston, Alexandre N. Sobolev
Functionalization of deep-cavity cavitands
Srinivasan Kannupal, Zachary R. Laughrey, Bruce C. Gibb
Divergent evolution of deep-cavity cavitands
Melissa J. Latter, Bruce C. Gibb
Modulating conformational dynamics of a cavitand using an external stimulus
Zhiqing Yan, Yuning Chang, Veselin Maslak, Dennis Mayo, Jovica D. Badjic
Complex interlocked architectures using olefin metathesis
Erin N. Guidry, Robert H. Grubbs
Highly convergent synthesis of rotaxanes via click chemistry
William R. Dichtel, Ognjen S. Miljanic, Jason M. Spruell, James R. Heath, J. Fraser Stoddart
Catenanes by click chemistry
Ognjen S. Miljanic, J. Fraser Stoddart, William R. Dichtel
Micellar, submicellar aggregates and non-micellizing hydrophobic ion effects upon the basic hydrolysis of 2-(3-iodophenoxy)quinoxaline
Angela Cuenca
Design and synthesis of highly fluorescent cobalamin analogs for cancer imaging
Manfai Lee, Charles B. Grissom
Practical applications of a “high pressure” chemical reactor for small-scale laboratory synthesis and process development
Kenneth J. James, Kenneth R. Krewson
High-throughput crystallization: Importance in process research and drug development
Arlene E. McKeown, Jennifer R. Chilenski, Louis S. Crocker, David J. Mathre, Vicky K. Vydra
Practical asymmetric synthesis of a γ-secretase inhibitor exploiting substrate-controlled intramolecular nitrile oxide-olefin cycloaddition
Steven F. Oliver, Jeremy P. Scott, Karel M. J. Brands, Sarah E. Brewer, Antony J. Davies, Andrew D. Gibb, David Hands, Stephen P. Keen, Faye J. Sheen, Robert D. Wilson, Robert A. Reamer, Ulf-H. Dolling
Efficient and practical synthesis of (R)-2-methylpyrrolidine
Dalian Zhao, Jeffrey T. Kuethe, Michel Journet, Zhihui Peng, Guy R. Humphrey
Synthesis of new class of indole compounds as non-imidazole histamine H-3 antagonists
Yi-Yin Ku, Yu-Ming Pu, Tim Grieme, Timothy A. Esbenshade, Marlon Cowart
Bismuth-catalyzed oxidation of olefins to enones using t-butyl hydroperoxide
Jorge A. R. Salvador, Samuel M. Silvestre
Process and intermediates for the preparation of functionalized imidazo[1,2-a]pyridines
Thomas Fuchß, Wolf-Rüdiger Ulrich, Christian Scheufler, Jörg Senn-Bilfinger
Efficient synthesis of 2-bromo-3-aroyl-benzothiophene
Fuyao Zhang, David Mitchell, Tony Y. Zhang
Practical synthesis of aminophenols using cyclohexanedione and amine
Shinji Aki, Hiroshi Kiyokawa, Yoshihisa Tanada, Jun-ichi Minamikawa
Synthesis of p38 MAP kinase inhibitor MK-0913 using naphthyridone N-oxide as a chemoselective control toward Grignard addition
John Y. L. Chung, Raymond J. Cvetovich, Joseph S. Amato, Fuh-Rong Tsay, Mark McLaughlin, Steven Weissman, Daniel Zewge, Mark Jensen
Practical synthesis of p38-MAPK inhibitor LY2228820-dimesylate
Zhonghui Wan, Chauncey Jones, Tony Y Zhang
Preparation and biological activity of phosphonic acid-containing MPA analogs as potent IMPDH II inhibitors
Michael Mertzman, Jennifer Zhang, Maria Fardis, Lee Chong, William J. Watkins, Ameneh Zeynalzadegan, Wei Huang
Efficient access to pharmaceutically important heterocycles
Mark McLaughlin, Michael Palucki, Ian W. Davies
Synthesis of N-alkyl-N-alkyloxycarbonylaminomethyl chlorides and soft alkylation of thiol, imide, phenolic and carboxylic acid containing drugs
Susruta Majumdar, Kenneth B. Sloan
Mild and direct conversion of quinoline N-oxides to 2-amidoquinolines with primary amides
Michel Couturier, Timothy D. White, Kris N. Jones, Laurence Caron, Stephanie Tumidajski
One-step procedure for the preparation of Boc-L-Dopa tetrabutylammonium salt
Toño Estrada, Suresh Manthati, Stephen P. Raillard
Understanding the formation and control of impurities in process development of Reyataz
Ming Z. Yang, Bruce T. Lotz, Janak Singh, Thomas P. Kissick, Sushil K. Srivastava
Horner-Wittig approach to exocyclic alkenes: Application to the synthesis of mineralocorticoid receptor (MR) antagonists
James A. Aikins, Marvin M. Hansen, Ryan Linder, Tony Y Zhang
Stereoselective synthesis of exocyclic alkenes via a double Heck reaction: Application to the synthesis of MR (mineralocorticord receptor) antagonists
John R. Rizzo, Tony Y. Zhang
Probe for distinguishing mechanisms in reactions of aldehydes with hypochlorite
William H. Hendrickson, Quang N. Nguyen, Shoichiro A. Tanaka
Palladium(II)-promoted Cope rearrangement
Matthew R. Siebert, Dean J. Tantillo
Mechanistic studies of an intramolecular nucleophile-catalyzed bis-cyclization process: Asymmetric synthesis of carbocycle and heterocycle-fused-β-lactones
Henry Nguyen, Huda Henry-Riyad, Gil Ma, Changsuk Lee, Daniel Romo
Mechanistic study of the (salen)chromium(III)/DMAP-catalyzed synthesis of 5-substituted oxazolidinones from carbon dioxide and aziridines
Aaron W. Miller, Frederick P. Arnold Jr., SonBinh T. Nguyen
General base-catalyzed ring-closure reactions to 5-cyanouracils: Kinetic and mechanistic studies
Kuangsen Sung, Pin-Mei Huang, Bo-Ren Zhuang
The road not taken: Rethinking aspernomine biosynthesis
Gregory A. Ho, Dean J. Tantillo
Mechanistic studies on diazocinone-forming cyclizations
Michael W. Lodewyk, Dean J. Tantillo
π-π Interaction in heterocyclic molecules
Abhijit Mitra, Joseph F. Capitani, Prantik Kundu, Christina Bergonzo, Libero Bartolotti, Pamela J. Seaton
The effects of dipolar resonance and tautomer contributions from alkyl amide solvents on the dispersion of single-wall carbon nanotubes
Brian Landi, Patrick Denno, Ryne P. Raffaelle, Nathan Darling, James J. Worman
Computational study of halomethyllithium carbenoid mixed aggregates with lithium halides
Lawrence M. Pratt, Shayla Merry
Computational study of the origin of diastereoselectivity in the base-catalyzed Staudinger synthesis of ß-lactams
Claude Y. Legault, K. N. Houk
Mechanistic investigation using density functional theory: The reactions of glycosyl iodides with oxa- and thiocycloalkanes
Dan Willenbring, Dean J. Tantillo
Quantum mechanical investigations into the mechanism of molybdenum-catalyzed asymmetric allylations
Jennifer Anne Robbins Luft, Zhi-Xiang Yu, David L. Hughes, Guy C. Lloyd-Jones, Shane Krska, K. N. Houk
Quantum chemical studies on trichodiene biosynthesis
Young J Hong, Dean J. Tantillo
Electronic effects on the cis to trans epimerization of Pictet-Spengler produced 1,2,3,4-tetrahydro-β-carbolines
Michael L. Van Linn, Dongmei Han, Hephzibah J Kumpaty, F. Holger Försterling, Jeffrey R. Deschamps, James M. Cook
Bond shifting in [12]-, [14]-, and [16]annulene: A new paradigm for thermal cis/trans isomerization
Claire Castro, William L. Karney, Joseph F. Moll, Ryan P. Pemberton
Photophysical studies in the solid state using transmission spectroscopy
Khin Kein Chin, Arunkumar Natarajan, Miguel A. Garcia-Garibay
Diethylenetriamine-substituted naphthalimide fluoroionophores
Anastasia V. Skobeleva, Jeffrey E. Elbert
Comprehensive study of the fs and ns photophysical properties of embedded thiophenes as a function of thiophene orientation
Brigitte Wex, Bilal R. Kaafarani, Evgeny O Danilov, Douglas C. Neckers
Isolation and characterization of photoproducts resulting from the irradiation of N-butyl-4-butylamino-1,8-naphthalimide
Brent A. Ristow, Ronald E. Utecht
Electronic effects on the photorelease of fluorinated p-hydroxyphenacyl caged substrates
Kenneth F. Stensrud, Richard S Givens
Ultrafast study of para-biphenyldiazomethane and para-biphenylcarbene
Jin Wang, Gotard Burdzinski, Terry L. Gustafson, Matthew S. Platz
Synthesis and two-photon induced Wolff rearrangment of 2-diazo-1,3-diketone with high two-photon absorption cross section
Nurtay K. Urdabayev, Vladimir V. Popik
Triplet sensitized photolysis of azidoarylketones: Intramolecular energy transfer vs. intramolecular H-atom abstraction
Jagadis Sankaranarayanan, Sivaramakrishnan Muthukrishnan, James Hale, Sarah M. Mandel, Pradeep N. D. Singh, Bruce S. Ault, Anna D. Gudmundsdottir
Detection of triplet vinyl nitrene
Sridhar Rajam, Abhijit V. Jadhav, Ahleah C Rohr, Pradeep N. D. Singh, Anna D. Gudmundsdottir
On the restricted rotation of cis-1,3-diphenyltriazenes: A structure-reactivity correlation study
Mónica Barra, Herlina Lim
Microheterogeneous distribution of singlet oxygen within block copolymer micelles
Matthew Grandbois, Kristopher McNeill
Highly selective transformation of olefin to ketone by visible light within zeolite Y
Yasuhiro Shiraishi, Takayuki Hirai
Highly selective photocatalytic epoxidation of olefins on Ti-containing silica with molecular oxygen
Yasuhiro Shiraishi, Masatsugu Morishita, Takayuki Hirai
Modeling the potential energy surface of thiophene-S-oxide and selenophene-Se-oxide deoxygenation
Stacey A. Stoffregen, Pearl Dickerson, William S. Jenks
Origins of selectivity in pericyclic reaction cascades for the synthesis of gambogin and lateriflorone
Amy E. Hayden, Hao Xu, K. C. Nicolaou, K. N. Houk
Understanding stereoselectivity in the boron aldol reaction of methyl ketones
Robert S. Paton, Jonathan M Goodman

Symposium Grid -- Division of Organic Chemistry -- Session Listing

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006