Session: Designing Multiple Ligands


MEDI		Monday, 11 September 2006

9:00 AM-12:30 PM Moscone Center -- Room 102, Oral
Designing Multiple Ligands

Organizers:	J. Richard Morphy Kenneth A. Jacobson
9:00 AM	262	Selectively non-selective drugs ("Magic Shotguns") vs. selective drugs ("Magic Bullets") for CNS disorders Bryan L Roth
9:35 AM	263	Synthesis, SAR and biological properties of 1-heteroaryl-4-[ù-(1H-indol-3-yl)-alkyl]-piperazines, novel potential antipsychotics combining potent Dopamine D2 receptor antagonism with potent Serotonin reuptake inhibition Pieter Smid, Hein K. A. C. Coolen, Rolf van Hes, Chris G. Kruse
10:10 AM	264	Designing multiple-acting ligands: How hard could that be !? Zoran Rankovic, J. Richard Morphy
10:45 AM	265	Tissue targeting with bivalent ligands selective for G protein receptor-coupled heterodimers: Opioid receptors as proof of concept Philip S. Portoghese
11:20 AM	266	Angiogenesis: Using focused diversity to develop specific inhibitors of VEGFR-2 with in vivo activity Alex S. Kiselyov
11:55 AM	267	Development of dual-acting benzofurans and benzomorpholines as thromboxane A₂ receptor antagonists and prostacyclin receptor agonists Michihiro Ohno, Mitsuko Miyamoto, Takahiro Takeda, Yoichiro Tanaka, Kei Makita, Kazuhiro Hoshi, Naohiro Yamada, Atsushi Ohtake