ORGN 788 |
Several small molecules that can effectively bind to Tat, a transactivator protein in the HIV replication cycle, are of interest at the cellular level for the potential use as drugs against HIV. Herein, details of the synthesis of potential Tat-inhibitors that can bind arginine residues of the Tat protein are presented.
|
|
Total Synthesis, Materials, Molecular Recognition, Process R&D, and Physical Organic Chemistry
8:00 PM-10:00 PM, Wednesday, 13 September 2006 Moscone Center -- Hall D, Poster
Division of Organic Chemistry |
