ORGN 525 |
| Tetracationic bisviologen cyclophane has been found to be an efficient additive in promoting aziridination of imines with phenyldiazomethane at room temperature. Both electron-rich and electron-deficient imine substrates were tested and found to undergo aziridination. A competition experiment with a known guest of the cyclophane significantly slowed the initial rate of reaction. A series of viologen additives were screened to probe the nature of catalysis. Comparison of the viologens reveals the tetracationic cyclophane to be the most efficient.
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New Reactions and Methodology, Heterocycles and Aromatics, Bioorganic Chemistry
8:00 PM-10:00 PM, Tuesday, 12 September 2006 Moscone Center -- Hall D, Poster
Division of Organic Chemistry |
