Asymmetric oxidative Pd(II) catalysis

ORGN 201

Kyung Soo Yoo, kyungsoo@usc.edu, Cheol Hwan Yoon, cheolhwan.yoon@usc.edu, and Kyung Woon Jung, kwjung@usc.edu. Department of Chemistry, University of Southern California, 837 Bloom Walk, LHI 132, Los Angeles, CA 90089
Recently, we found that the reaction between phenylboronic acid and α-methyl unsaturated alkene, such as trans-2-methyl-2-buteneal produced the rearrangement compound in general yields due to Pd-H β-elimination. With a palladium-pyridinyloxazoline chiral catalyst complex gave good yields and reasonably good enantioselectivity for the catalyzed intermolecular asymmetric arylation of highly substituted α,β-unsaturated carbonyl compounds.

 

Asymmetric Reactions and Syntheses, Metal-Mediated Reactions, Combinatorial, Parallel, and Solid-Phase Chemistry
8:00 PM-10:00 PM, Sunday, 10 September 2006 Moscone Center -- Hall D, Poster

Division of Organic Chemistry

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006