Molecular Solomon links

ORGN 785

Cari D. Pentecost1, Kelly S. Chichak1, Andrea J. Peters1, Stuart J Cantrill, cantrill@chem.ucla.edu2, and J. Fraser Stoddart, stoddart@chem.ucla.edu1. (1) California NanoSystems Institute and Department of Chemistry and Biochemistry, University of California, Los Angeles, 405 Hilgard Avenue, Los Angeles, CA 90095-1569, (2) Department of Chemistry and Biochemistry, University of California, Los Angeles, 607 Charles E. Young Dr. East, Los Angeles, CA 90095-1569
The four-noded, two-component link known as the Solomon Knot (SK) has been said to contain all of the wisdom of King Solomon. For several centuries, many cultures have adopted this emblem to represent knowledge. SKs can be found in many different settings from adorning the crowns of African kings to being incorporated into the architecture of university libraries. With the advent of new synthetic methodologies that are advancing under the umbrella of template-directed synthesis, chemists are beginning more and more to appreciate the subtleties of topologically interesting structures, and have consequently pursued the synthesis of their molecular analogues. For example, the complete molecular construction of the Borromean ring (BR) topology and its derivatives has been achieved successfully from 18 individual components under strict dynamic covalent, coordinative and supramolecular control. In a similar fashion, we have recently obtained the SK molecular topology from 12 individual components, resulting from mixing Cu(II) and Zn(II) metal templates in a 1:1 ratio, leading to the formation (Box) of the SKs in preference to the BRs.

 

Total Synthesis, Materials, Molecular Recognition, Process R&D, and Physical Organic Chemistry
8:00 PM-10:00 PM, Wednesday, 13 September 2006 Moscone Center -- Hall D, Poster

Division of Organic Chemistry

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006