Supramolecular aggregation of novel amphiphiles

ORGN 283

Kevin L. Caran, carankl@jmu.edu, Cobbina K. Benson-Adjei, bensoncx@jmu.edu, Ashleigh R. Borges, David M. Crizer, crizerdm@jmu.edu, Kristen R. Donnelly, donnelkr@jmu.edu, Nicholas P. Henrich, Angela M. Middleton, middl2am@jmu.edu, and Karolina Z. Roszak, roszakkz@jmu.edu. Department of Chemistry, James Madison University, MSC 4501, Harrisonburg, VA 22807
Recent work in our laboratory has focused on the preparation of new amphiphiles in an effort to expand the variation and utility of supramolecular aggregation in aqueous and/or non-polar environments. Novel structures include (1) biscationic single-chained amphiphiles with varied hydrophobic chain lengths, (2) partially fluorinated structures and (3) amphiphilic catenanes. Progress on the synthesis of these molecules as well as aggregation studies on the final products using NMR, surface tensiometry, differential scanning calorimetry, light microscopy and electron microscopy will be presented.