ORGN 880 |
| Cyclopeptide alkaloids are natural products that have been isolated from the leaves, stem bark, root bark, and seeds of a wide variety of plant species throughout the world. Paliurine F is one among the 250 cyclopeptide alkaloids: it has been isolated in 2000 and possesses an interesting antimalarial activity. An original, general and straightforward strategy en route to cyclopeptide alkaloids, and more specifically paliurine F, will be presented with emphasis on the installation of the aryl ether and enamide linkages as well as strategies envisioned for macrocyclization.
|
|
Proteins, Peptides, Amino Acids, and Enzyme Inhibitors
8:00 AM-12:00 PM, Thursday, 14 September 2006 Moscone Center -- Room 131, Oral
Division of Organic Chemistry |
