Novel synthesis of 2-alkenyl and 2-arylbenzimidazoles

ORGN 267

Jeremiah W. Hubbard, jhubbar4@yahoo.com, Björn C. G. Söderberg, bjorn.soderberg@mail.wvu.edu, and Adam M. Piegols, apiegols@mix.wvu.edu. Department of Chemistry, West Virginia University, PO Box 6045, Morgantown, WV 26505
Synthesis of 2-alkenyl and 2-arylbenzimidazoles, having a variety of functional groups, has been accomplished via a novel palladium catalyzed reductive N-heteroannulation of 2-nitro-N-alkyl or N-benzyl benzenamines. The cyclization precursors are readily prepared from commercially available compounds by a variety of methods.