ORGN 881 |
| The fight against bacterial infection represents one of the continuing challenges in medicine. Orienticin C belongs to the vancomycin family of antibiotics and its complex molecular architecture makes its synthesis a real challenge. Herein the total synthesis of Orienticin C aglycone is described, in which ruthenium-mediated intramolecular etherification is used as a key step for the construction of the biaryl ether linkages.
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Proteins, Peptides, Amino Acids, and Enzyme Inhibitors
8:00 AM-12:00 PM, Thursday, 14 September 2006 Moscone Center -- Room 131, Oral
Division of Organic Chemistry |
