ORGN 768 |
| Hydrophobic interactions can play a large role in the binding of small organic molecules in biological systems. We present a water-soluble synthetic receptor with four benzoate groups attached to the open end. These groups control the rate of guest exchange by acting as revolving doors. Binding properties were studied using 1-D and 2-D NMR methods. The nature of the receptor's inner surface was investigated via UV/Vis and time-resolved fluorescence spectroscopy. |
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Total Synthesis, Materials, Molecular Recognition, Process R&D, and Physical Organic Chemistry
8:00 PM-10:00 PM, Wednesday, 13 September 2006 Moscone Center -- Hall D, Poster
Division of Organic Chemistry |