Silylene-mediated synthesis of cyclic silyl imines and enamines from nitriles and alkynes: Subsequent functionalization of azasilacyclopentadienes

ORGN 368

Laura L. Anderson, landers1@uci.edu and K. A. Woerpel, kwoerpel@uci.edu. Department of Chemistry, University of California, Irvine, Irvine, CA 92697
Regioselective insertions of nitriles into the more highly substituted C-Si bond of di-tert-butylsilirenes provide azasilacyclopentadienyl imines and enamines. Further functionalization of these compounds and application to the stereoselective synthesis of amines will be discussed.

 

New Reactions and Methodology
8:00 AM-12:00 PM, Tuesday, 12 September 2006 Moscone Center -- Room 133, Oral

Division of Organic Chemistry

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006