ORGN 425 |
| Acceleration of the development time line for the discovery and development of new pharmaceutical agents and the requirement for reproducible and validated manufacturing processes in the pharmaceutical industry has lead to an increase application of real-time monitoring of chemical processes. One of the most versatile technologies in this area is mid-IR owing to its specificity and adaptability to manufacturing environments. In the development area, real-time monitoring of the concentration of reagents, intermediates and products, rapidly provides fundamental understanding of the underlying mechanisms and kinetics for organic and inorganic reactions. This presentation will describe two case studies in the application of mid-infrared spectroscopy to process development. The examples provided cover the spectrum of development – laboratory, preparatory and pilot plant scales |
|
Process R&D and Practical Syntheses of Medicinal Agents
1:00 PM-4:40 PM, Tuesday, 12 September 2006 Moscone Center -- Room 132, Oral
Division of Organic Chemistry |